|
KMID : 0357520160390020143
|
|
Journal of Radiological Science and Technology
2016 Volume.39 No. 2 p.143 ~ p.148
|
|
|
Observer Variation Factor on Advanced Method for Accurate, Robust, and Efficient Spectral Fitting of java Based Magnetic Resonance User Interface for MRS data analysis
|
|
Lee Suk-Jun
Yu Seung-Man
|
|
|
Abstract
|
|
|
|
The purpose of this study was examined the measurement error factor on AMARES of jMRUI method for magnetic resonance spectroscopy (MRS) quantitative analysis by skilled and unskilled observer method and identified the reason of independent observers. The Point-resolved spectroscopy sequence was used to acquired magnetic resonance spectroscopy data of 10 weeks male Sprague-Dawley rat liver. The methylene protons ((-CH2-)n) of 1.3 ppm and water proton (H2O) of 4.7 ppm ratio was calculated by LCModel software for using the reference data. The seven unskilled observers were calculated total lipid (methylene/water) using the jMRUI AMARES technique twice every 1 week, and we conducted interclass correlation coefficient (ICC) statistical analysis by SPSS software. The inter-observer reliability (ICC) of Cronbach’s alpha value was less than 0.1. The average value of seven observer’s total lipid (0.096±0.038) was 50% higher than LCModel reference value. The jMRUI AMARES analysis method is need to minimize the presence of the residual metabolite by identified metabolite MRS profile in order to obtain the same results as the LCModel.
|
|
|
KEYWORD
|
|
|
magnetic resonance spectroscopy , metabolite , pulse sequence
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|